Stem Cell Transplant-Types, Success Rate, Survival Rate and Best Hospitals in India

Stem Cell Transplant in India
Stem Cell Transplant in India

Stem cell transplant (SCT) is a cure available for several diseases and all of these treatments are done at economical prices in India. But survival and success rate of stem cell transplant (SCT) procedure has its dependency on several factors like the stage of the disease, type of disease, an age of the patient, and health condition of the patient etc.

Stem Cell Transplant (SCT) in India:

Stem cell transplant (SCT) turns out to be a life-saving procedure for several malignant and non-malignant diseases. The number of stem cell transplants (SCT) being done is more than 40,000 across the world. India is slowly contributing toward this huge number of stem cell transplants (SCT) done every year. Over the past few years, India has become equipped with facilities in its hospitals to be able to handle all sort of complicated cases requiring a stem cell transplant (SCT). Learn More About Stem Cell Transplant.

What are the types of Stem Cell Transplant (SCT)?

There are several types of stem cell transplant (SCT) available which are used to treat different malignant and non-malignant diseases. Every disease cannot be treated with one particular type of stem cell transplant (SCT) and neither can evert SCT be applicable in every case. Every patient has a certain different set of requirements. But amongst all types of SCT allogeneic transplant is the most common form of SCT which is even used to treat several forms of leukemia-like AM and several other disorders.

Following are the main types of stem cell transplant (SCT) available to cure diseases:

•   Auto or Autologous stem cell transplant (SCT)

This type of transplant uses the stem cells of the patient to carry out the transplant successfully. In this case, some of the healthy stem cells of the patient are extracted and preserved to be used during transplant. After that chemotherapy or radiation therapy is initiated to kill and destroy the malignant stem cells of the body. This method is applied to treat several conditions like multiple myeloma, and even in relapse of Hodgkin and non-Hodgkin lymphomas.

The main advantage of this transplant method is lower chances of graft rejection or complete rejection, graft-versus-host disease, engraftment also occurs quickly and overall side effects and complications are even less.

But this stem cell transplant (SCT) method has a limitation that at times, some of the cancer cells might remain, even after the complete procedure. Since the cancer killing effect appears only during chemotherapy or radiation. In rare cases, some of the cancer cells are missed during chemo.

•   Allo or Allogeneic stem cell transplant (SCT)

In this type of transplant, a mandatory requirement is a donor from whom stem cells can be obtained. But a donor needs to have a matching HLA with the patient otherwise the person is not fit for being a donor. A donor can be a relative or non-relative but a matching one. This method is used for several diseases like many aggressive lymphomas, leukemias, and even in failed cases of autologous transplants.

Its advantage is that the new stem cells which are transplanted are completely healthy and cancer-free. This also reboots the immune system once again and even the cancer killing effect continues after the stem cell transplant (SCT).

But the main disadvantage allogeneic stem cell transplant (SCT) holds is a rejection or denial of the transplanted stem cells, slow engraftment, and more complications like GVHD etc.

What is the Success rate of Stem Cell Transplant (SCT) in India?

SCT in India has sufficiently good success rates and this is another reason besides the economic price for medical tourism. Indian hospitals are equipped in terms of equipment as well as experienced internationally well-trained doctors and other staff members to deal with conditions seeking SCT as a treatment option. Several types of research are being done to evaluate and maintain data on the success rate of the different set of cases of SCTs done every year in India. Since every case requiring SCTs is not the same and dozens of them involves complications which also require some additional treatments as well. But most of the cases are a complete success with rare a percentage of nearly less than 30 percent touching a failure or requiring a re-transplant.


What is the Survival rate of patients have undergone Stem Cell Transplant (SCT) in India?

Stem cell transplant (SCT) improves the chances of survival of a patient rather than without it. Since SCT is the commonly opted method to treat and cure such complicated diseases or cancers which cannot be done with drugs, chemotherapies, and radiations. Several studies reveal that a person can sustain for more than 3 years and even more if no remissions appear. Especially in young patients, SCT can be entirely life-saving and the patient can lead a sufficiently healthy life for long after the procedure.


Which is the best hospital for Stem Cell Transplant (SCT) in India?

Every hospital in India is fully equipped and has the potential deal with every sort of SCT cases.  Every case has some specific requirements and you must always look for the hospital as per that. Every hospital in India has the best of oncologists, hematologists, and other doctors. But in order to find your best the hospital, you may let us know your requirements via a live chat available on the blog portal.


Related FAQs:

1) Q: Is Stem Cell Transplant (SCT) really cure cancer? 

A: Stem cell transplant (SCT) is capable of treating several variable diseases like aplastic anemia, sickle cell anemia, thalassemia, myeloma, lymphomas, leukemias- AML, ALL, CML, neuroblastoma etc. But in most of the cases stem cell transplant (SCT) is taken into consideration when all other lines of treatment like chemo, radiation, immune targeting, drugs etc failed to achieve a firm improvement and cure of the condition. So SCT can be considered as an option to cure such diseases of the root. But still, every case might be different depending upon the facts and certain risks and involved complications which must be discussed with the doctor prior to starting with the treatment. Learn More about the diseases can be cured with a Stem Cell Transplant.


2) Q: How long a cancer patient live after Stem Cell Transplant (SCT)?

A:  Any cancer patient treated with stem cell transplant (SCT) can sufficiently survive for 3 to 5 years or longer if no remissions appear.


3) Q: Is it safe to donate Stem Cell?

A: Yes, it is completely safe to volunteer and be a donor for the stem cell transplantation. Instead, it can help another person to survive through the tough time and live longer. Moreover, stem cell donation is done under the anesthesia effect or even cells can be obtained from the peripheral blood after a filtration process without even requiring any anesthesia or recovery period for a donor. A donor can be any related or family member, an unrelated person, a related haploidentical person from the family.

Bone Marrow Transplant-Types, Success Rate, Survival Rate and Best Hospitals in India

Bone Marrow Transplant (BMT)-Types, Success Rate, Survival rate and best hospitals in India
Bone Marrow Transplant (BMT)-Types, Success Rate, Survival rate and best hospitals in India

India has become a hub for a bone marrow transplant (BMT) over the last few years. The economical pricing of bone marrow transplant (BMT) procedure with a good survival rate and success rate offered by the Indian hospitals has led to this change. The medical tourism in India is increasing eventually with its rising fame in several treatment options.


Bone Marrow Transplant (BMT) in India:

Every hospital or center offering bone marrow transplant in India is facilitated with ultra-modern infrastructure along with widely experienced and even some internationally trained doctors and staff. Every type of bone marrow transplant (BMT) is available in India and the hospitals are fully equipped with all necessary equipment like a proper radiation and oncology unit for total body radiation, and chemotherapy drugs and equipments. Both autologous, as well as allogeneic bone marrow transplant (BMT), can be done efficiently as per the case requirement by utilizing bone marrow, cord blood stem cells, and peripheral stem cells. Several diseases like bone marrow disorders, leukemias, lymphomas, aplastic anemia sickle cell anemia, multiple myelomas, thalassemia, pediatric tumors etc can be treated by bone marrow transplant (BMT). Learn More about Bone Marrow Transplant.


What are the types of Bone Marrow Transplant (BMT)?

Every case has some certain specifications and limitations as well. Which can either be treated by one particular BMT option or at times different options can be applicable but your doctor can decide the best applicable option of BMT.

Following are the few options available in bone marrow transplant (BMT):

Autologous bone marrow transplant involves using the stem cells obtained from the patient’s own bone marrow. This is done in those patients who still possess some healthy stem cells. Before destroying the cancer cells by radiation or chemotherapy those healthy stem cells can be extracted from the patient and preserved under the required nominal conditions. Later those stem cells of the patient can be injected into the patient after complete irradiation of the cancerous cells. This method has fewer complication chances as rejection and graft failure chances are minimal.

Allogenic BMT is done preferably for some diseases. In this, a donor is required for obtaining stem cells. Allogeneic transplants require a matching donor with respect to the tissue or HLA matching. This type of bone marrow transplant (BMT) is applicable in cases where a patient’s own stem cells are completely damaged or destroyed to be used for autologous transplant. These transplants are prone to certain complications like graft-versus-host disease and other complications like graft failure, complete rejection etc. Finding a suitable donor can also be a tedious task. A donor can be a related or unrelated but with a complete match. Although getting a related match from a brother or sister poses lesser complications than an unrelated match. Since it further reduces the risk of rejection chances etc.

A donor undergoes a process of stem cell harvesting or stem cell collection. These days a new method of storing stem cells of newborn includes umbilical cord or placenta preservation in cord blood banks, such stem cells are not specialized so requires a minimal matching in comparison to adult stem cells.

There are different types of allogeneic transplants available based on the donor cells source.

They are listed below:

Related donor allogeneic transplant: Many relatives can be a source of stem cell donor but the ideal match must opt as it reduces the risk of complications to a minimum. Also, siblings are normally found to be a certain close match as a donor and identical twins can be an added advantage in such case.

Matched unrelated donor allogeneic transplant: These days there are certain international registrations done for donors. So in cases, where related matching donors are not available then these donor banks can be approached with global registrations to obtain a matching donor. It is a little tedious and time-consuming task but at times it can be the only hope for a perfect donor.

Half-matched related or family member donor allogeneic transplant: These days haploidentical bone marrow transplants (BMT) are routinely done in cases where more than 50 percent of a match is not available. In those cases, siblings, as well as parents, turn out to be a Hal-match or 50 percent match also known as the haploid match.

Cord blood transplants: This is the most recently available option for a bone marrow transplant (BMT). Especially in cases where even a minimum matching donor is not available. The cord stem cells obtained from the parental cord of the newborn are immature unlike in any adult stem cells, therefore, it does not even require a very close match with the recipient’s tissues.

What is the Success rate of Bone Marrow Transplant (BMT) in India?

Bone marrow transplant (BMT) has a predictable survival rate of nearly more than 60 percent. Every bone marrow transplant (BMT) case survival varies depending upon the type of transplant chosen like allogeneic or autologous. Even the complete replacement or removal of diseases marrow cells is not enough sometimes although it does efficiently work in most of the cases of transplant. The success and survival rates of any bone marrow transplant (BMT) depends greatly on patients condition and requirement. Bone marrow transplant (BMT) does cure some of the diseases and helps in extending life and improves the quality of life as well. But in some rare cases treating one disease leads to remission of another during or after the treatment. But those risks and complications and their chances can be discussed with a specialized doctor before undergoing a bone marrow transplant (BMT). Learn More About the Success Rate of BMT.


What is the Survival rate of patients have undergone Bone Marrow Transplant (BMT) in India?

People undergoing a bone marrow transplant (BMT) in India have a good survival rate. India has emerged as a global hub for several affordable but highly effective treatments. So any treatment in India including a bone marrow transplant (BMT) does have a good survival rate like in any other standard developed country but they charge too much unlike Indian economic prices for BMT. Several statistical data has been accumulated to date to support good survival rates offered by Indian BMT done for several diseases and age group patients. A relevant data states that nearly 30% to 40% of above 60 age group patients do survive more than 3 years after BMT done in India. The survival chances increase if younger is the patient age who are being treated and early is the diagnosis stage of the disease. Further, no reoccurrence until 2 years after BMT, even improves the chances of disease-free and longer survivals. Learn More About the Survival Rate of BMT Patients


Which is the best hospital for Bone Marrow Transplant (BMT) in India?

Every hospital is good in its own way of offering facilities and treatment in India. But in order to find the best suitable as per your requirement reach us on the live chat and we can help you provide a list of best hospitals to choose. Several private hospitals offer a variety of prices for a bone marrow transplant. But several factors like the involvement of donor, sort of disease for which treatment is done, and the age of the patient plays an important role in setting up a probable price for the treatment. Learn More About the Hospitals have the highest Success Rate for BMT.


Related FAQs:

1) Q: Is Bone Marrow Transplant (BMT) really cure cancer? 

A: Bone marrow transplant (BMT) can certainly help in treating several diseases like cancers, leukemia, myelomas etc. But a BMT as a definite cure can only happen in some cases which never relapse otherwise chances of relapse sometimes affect the complete curing ability.

2) Q: How long a cancer patient live after Bone Marrow Transplant (BMT)? 

A: Patients survive long enough after bone marrow transplant (BMT). For eg: a person can survive for nearly five years after BMT if no complication arises and this survival even increases for the next 15 years and more if no relapse of the disease appears.

3) Q: Is it safe to donate bone marrow?

A: It is completely safe to donate the bone marrow and the procedure is done under the effect of anesthesia. The entire procedure is done under complete supervision in a hospital and requires a few days of recovery.