Bone Marrow Transplant-Types, Success Rate, Survival Rate and Best Hospitals in India

Bone Marrow Transplant (BMT)-Types, Success Rate, Survival rate and best hospitals in India
Bone Marrow Transplant (BMT)-Types, Success Rate, Survival rate and best hospitals in India

India has become a hub for a bone marrow transplant (BMT) over the last few years. The economical pricing of bone marrow transplant (BMT) procedure with a good survival rate and success rate offered by the Indian hospitals has led to this change. The medical tourism in India is increasing eventually with its rising fame in several treatment options.

Bone Marrow Transplant (BMT) in India:

Every hospital or center offering bone marrow transplant in India is facilitated with ultra-modern infrastructure along with widely experienced and even some internationally trained doctors and staff. Every type of bone marrow transplant (BMT) is available in India and the hospitals are fully equipped with all necessary equipment like a proper radiation and oncology unit for total body radiation, and chemotherapy drugs and equipments. Both autologous, as well as allogeneic bone marrow transplant (BMT), can be done efficiently as per the case requirement by utilizing bone marrow, cord blood stem cells, and peripheral stem cells. Several diseases like bone marrow disorders, leukemias, lymphomas, aplastic anemia sickle cell anemia, multiple myelomas, thalassemia, pediatric tumors etc can be treated by bone marrow transplant (BMT). Learn More about Bone Marrow Transplant.

What are the types of Bone Marrow Transplant (BMT)?

Every case has some certain specifications and limitations as well. Which can either be treated by one particular BMT option or at times different options can be applicable but your doctor can decide the best applicable option of BMT.

Following are the few options available in bone marrow transplant (BMT):

Autologous bone marrow transplant involves using the stem cells obtained from the patient’s own bone marrow. This is done in those patients who still possess some healthy stem cells. Before destroying the cancer cells by radiation or chemotherapy those healthy stem cells can be extracted from the patient and preserved under the required nominal conditions. Later those stem cells of the patient can be injected into the patient after complete irradiation of the cancerous cells. This method has fewer complication chances as rejection and graft failure chances are minimal.

Allogenic BMT is done preferably for some diseases. In this, a donor is required for obtaining stem cells. Allogeneic transplants require a matching donor with respect to the tissue or HLA matching. This type of bone marrow transplant (BMT) is applicable in cases where a patient’s own stem cells are completely damaged or destroyed to be used for autologous transplant. These transplants are prone to certain complications like graft-versus-host disease and other complications like graft failure, complete rejection etc. Finding a suitable donor can also be a tedious task. A donor can be a related or unrelated but with a complete match. Although getting a related match from a brother or sister poses lesser complications than an unrelated match. Since it further reduces the risk of rejection chances etc.

A donor undergoes a process of stem cell harvesting or stem cell collection. These days a new method of storing stem cells of newborn includes umbilical cord or placenta preservation in cord blood banks, such stem cells are not specialized so requires a minimal matching in comparison to adult stem cells.

There are different types of allogeneic transplants available based on the donor cells source.

They are listed below:

Related donor allogeneic transplant: Many relatives can be a source of stem cell donor but the ideal match must opt as it reduces the risk of complications to a minimum. Also, siblings are normally found to be a certain close match as a donor and identical twins can be an added advantage in such case.

Matched unrelated donor allogeneic transplant: These days there are certain international registrations done for donors. So in cases, where related matching donors are not available then these donor banks can be approached with global registrations to obtain a matching donor. It is a little tedious and time-consuming task but at times it can be the only hope for a perfect donor.

Half-matched related or family member donor allogeneic transplant: These days haploidentical bone marrow transplants (BMT) are routinely done in cases where more than 50 percent of a match is not available. In those cases, siblings, as well as parents, turn out to be a Hal-match or 50 percent match also known as the haploid match.

Cord blood transplants: This is the most recently available option for a bone marrow transplant (BMT). Especially in cases where even a minimum matching donor is not available. The cord stem cells obtained from the parental cord of the newborn are immature unlike in any adult stem cells, therefore, it does not even require a very close match with the recipient’s tissues.

What is the Success rate of Bone Marrow Transplant (BMT) in India?

Bone marrow transplant (BMT) has a predictable survival rate of nearly more than 60 percent. Every bone marrow transplant (BMT) case survival varies depending upon the type of transplant chosen like allogeneic or autologous. Even the complete replacement or removal of diseases marrow cells is not enough sometimes although it does efficiently work in most of the cases of transplant. The success and survival rates of any bone marrow transplant (BMT) depends greatly on patients condition and requirement. Bone marrow transplant (BMT) does cure some of the diseases and helps in extending life and improves the quality of life as well. But in some rare cases treating one disease leads to remission of another during or after the treatment. But those risks and complications and their chances can be discussed with a specialized doctor before undergoing a bone marrow transplant (BMT). Learn More About the Success Rate of BMT.

What is the Survival rate of patients have undergone Bone Marrow Transplant (BMT) in India?

People undergoing a bone marrow transplant (BMT) in India have a good survival rate. India has emerged as a global hub for several affordable but highly effective treatments. So any treatment in India including a bone marrow transplant (BMT) does have a good survival rate like in any other standard developed country but they charge too much unlike Indian economic prices for BMT. Several statistical data has been accumulated to date to support good survival rates offered by Indian BMT done for several diseases and age group patients. A relevant data states that nearly 30% to 40% of above 60 age group patients do survive more than 3 years after BMT done in India. The survival chances increase if younger is the patient age who are being treated and early is the diagnosis stage of the disease. Further, no reoccurrence until 2 years after BMT, even improves the chances of disease-free and longer survivals. Learn More About the Survival Rate of BMT Patients

Which is the best hospital for Bone Marrow Transplant (BMT) in India?

Every hospital is good in its own way of offering facilities and treatment in India. But in order to find the best suitable as per your requirement reach us on the live chat and we can help you provide a list of best hospitals to choose. Several private hospitals offer a variety of prices for a bone marrow transplant. But several factors like the involvement of donor, sort of disease for which treatment is done, and the age of the patient plays an important role in setting up a probable price for the treatment. Learn More About the Hospitals have the highest Success Rate for BMT.

Related FAQs:

1) Q: Is Bone Marrow Transplant (BMT) really cure cancer? 

A: Bone marrow transplant (BMT) can certainly help in treating several diseases like cancers, leukemia, myelomas etc. But a BMT as a definite cure can only happen in some cases which never relapse otherwise chances of relapse sometimes affect the complete curing ability.

2) Q: How long a cancer patient live after Bone Marrow Transplant (BMT)? 

A: Patients survive long enough after bone marrow transplant (BMT). For eg: a person can survive for nearly five years after BMT if no complication arises and this survival even increases for the next 15 years and more if no relapse of the disease appears.

3) Q: Is it safe to donate bone marrow?

A: It is completely safe to donate the bone marrow and the procedure is done under the effect of anesthesia. The entire procedure is done under complete supervision in a hospital and requires a few days of recovery.

Where is low-cost bone marrow transplant surgery done in India? And what is the success rate?

Where is low-cost bone marrow transplant surgery done in India?
Where is low-cost bone marrow transplant surgery done in India?

The bone marrow transplant cost in India is highly cheap although the treatment is highly effective like the one provided in any developed country. A need of bone marrow transplant (BMT) might include several reasons starting from chronic diseases, infections, aplastic or sickle cell anemia, or big lymphomas, blood disorders like leukemia etc. all of these has one simple appearing but in a really complex solution of BMT. The bone marrow transplant cost in India might be variable but the average amount is still somewhere between 18 to 35 lakh which is comparatively cheaper and affordable. This economic average bone marrow transplant cost in India makes this place a destination for the treatment for world-wide patients across the globe.

Do the success rate of the bone marrow transplant varies as per its type or disease being treated for?

The bone marrow transplant cost in India as well as its success rate both are highly dependent upon what is the disease’s severity and type. Like autologous bone marrow transplant cost in India is lesser than the allogeneic bone marrow transplant cost in India. Because in autologous the healthy stem cell of the patient can be utilized for transplant unlike in the other case. Similarly in allogeneic dependency on donor and finding a right match can add up to the cost and even make success rate variable. Like there appears chances of rejection and GVHD in such cases.

Why is India a chosen place for bone marrow transplant?

The bone marrow transplant cost in India is so economic that India is becoming more and more popular for BMT these days. In the past few years, India has transformed into a low-cost BMT hub for several foreign patients. Every year several patients from countries like Oman, Iraq, Bangladesh, Srilanka, Kenya, Nepal, Myanmar, Nigeria etc are coming for medical tourism in India. The bone marrow transplant cost in India is far more reasonable than the prices offered by the UK, USA, Canada, and other developed countries. Besides, HLA identical sibling transplants Indian hospitals have massively started with new modern BMTs which are available worldwide with modern technology like cord blood transplant, unrelated donor matching transplants, and BMTs for leukemia in children and many immunodeficiency syndromes. Techniques involved during lymphoma treatments like total body radiations etc has also been incorporated in several well established Indian hospitals. So all these and economic bone marrow transplant cost in India is a center of attraction for all needy patients.

Related FAQs:

1) Q: Which malignant and non-malignant diseases can be treated with effective and economic bone marrow transplant cost in India?

A: A bone marrow transplant cost in India also varies depending upon the type it is treated for. Following are the few malignant and non-malignant diseases which can be treated by BMT:

BMT for malignant conditions includes Hodgkin’s and non-Hodgkin’s lymphoma; Acute myeloid leukemia, Chronic myeloid leukemia, Acute lymphoblastic leukemia, neuroblastoma, Multiple myelomas, Myelofibrosis etc.

BMT for Non-malignant conditions includes Sickle cell anemia, Aplastic anemia, Thalassemia, and Hemophagocytic syndrome etc.

2) Q: What happens if the blood cell count falls during any bone marrow disease?

A: A decrease in white blood cells impairs the body to fight against any infections, a lack of red blood cells provides insufficient oxygen supply to the body cells, and a decreased platelets count can cause excessive bleeding.

3) Q: What is an average bone marrow transplant cost in India?

A: The average bone marrow transplant cost in India varies between 18 to 35 lakh. It is a highly variable amount depending upon the type of hospital opted or the type of transplant you might have to undergo. A lower price than this is also offered by some of the Indian government tie up hospitals in India.

How much does bone marrow transplant procedure cost in India?

How much does bone marrow transplant procedure cost in India?
How much does bone marrow transplant procedure cost in India?

In the past few years the Indian Healthcare sector has experienced several ups and downs and going through all challenges and huge investments now India has transformed into a hub for all sort of medical treatments. The economic cost of high-quality medical treatments available in India is providing a cutting edge competition to several other countries in the healthcare sector. India has started an alliance with several countries to build up more trust and technology upon which people from the whole world can easily fall back.

Bone marrow transplant procedure requires a matching bone marrow. Although finding a matching donor is a big task and might consume a lot of money which can be saved otherwise in an autologous transplant. Upon an average, the bone marrow transplant procedure cost in India ranges between 18 lakh to 36 lakh. The pricing can even further go down to 8 lakh to 12 lakh in some government-run Indian hospitals offering bone marrow transplant procedure.

What makes the price differences vary of bone marrow transplant procedure in India?

The full and final cost of a bone marrow transplant procedure in India depends mainly on if you are getting an allogeneic or autologous transplant. In an allogeneic transplant bone marrow is obtained from a donor and this becomes one of the expensive types of transplants involving a hurdle of finding a matching donor as well. Another type of autologous transplant involves obtaining healthy stem cells of the patient which can be utilized for the transplant and this is one of the affordable options amongst bone marrow transplant procedures. 

The cost of the bone marrow transplant procedure offered by every country varies significantly. Currently, India is considered one of the most reliable in terms of pricing offered for the bone marrow transplant procedure. The Indian procedure pricing is nearly a fraction of the amount being charged in UK, and USA.

What includes the pre-procedure cost and post-procedure cost?

The pre-procedure cost of the bone marrow transplant procedure includes a list of several tests which are done to analyze the patient’s in-depth condition. This helps to make the patient prepare for the procedure in every aspect and also it helps the doctor to carry out the procedure in a precise way.

After the bone marrow transplant procedure is over the cost of in-hospital stay along with medications and complications in rare cases makes up the post-procedure cost. Every hospital in India takes preventive measures to avoid all sorts of infections during and after the procedure which leads to complications and hence increases the cost of an entire procedure.

Rest for the foreign patients, the travel and accommodation costs also add up to the main procedure cost. But still, the entire overall bone marrow transplant cost will be lesser than being charged in other developed countries.

Related FAQs:

1) Q: Which is the most commonly opted source in the bone marrow transplant procedure?

A: Transplant of stem cell has opted readily since it develops early and produces blood cells. It can also be easily extracted from the blood instead of relying on bone marrow.

2) Q: What all adds up in the bone marrow transplant procedure cost?

A: Besides, the transplant certain health check-ups and examination, a source of new cells, blood tests, aftercare, chemotherapy, and radiation therapy etc all adds up in the cost of the procedure.

3) Q: Is it mandatory to receive Chemotherapy before bone marrow transplant procedure?

A: It is not mandatory but instead it depends upon the condition of the patient and what the doctor decides is best for the patient. Usually either ablative or high dose therapy or mini-transplant or low dose chemo is given to the patients.

BMT in India- What difficulties patients have to face during treatment?

BMT in India- what difficulties patients have to face during treatment?
BMT in India- what difficulties patients have to face during treatment?

BMT in India is the procedure done in high numbers. This involves Indian as well as many foreign patients. In this procedure, replacement of the damaged bone marrow is done with such bone marrow stem cells which are healthy and efficient. A person must undergo a BMT in India if he or she is unable to make sufficient blood count and is looking for economic treatment or in order to combat any underlying disease of aplastic anemia, leukemia etc. The procedure of BMT in India is highly successful and is performed by skilled professionals in every hospital.

Why BMT is becoming an urgent need for the patient?

The survival of the person depends upon his body’s capability of fighting against infections and diseases. Whereas a damaged or malfunctioned bone marrow makes a person all these abilities to combat against diseases.  So it becomes mandatory for the person to seek treatment and get bone marrow transplant in such cases.

What you must look for in a matching donor during BMT in India?

Finding a donor during BMT in India can be a hurdle because donor registration in NOTTO or National Organ and Tissue Transplant Organization is not followed here. Moreover, India has very few donor registers and amongst all the reliable and oldest one is MDRI or Marrow Donor Registry India.

There are few tips to follow while finding a matching donor during BMT in India:

•   The age group of the donor must be between 18 to 50 with good health. The younger the donor the better it will be for the patient.

•   A donor must be free from any diseases like of cancer, cardiac, liver, kidney, diabetes, and even obesity etc.

•   A donor must also be free from any kind of high-risk viral diseases like AIDS etc.

India still requires a lot of awareness for the need of donor registration so as to motivate people to register once they turn eligible. Once this is done more and more lives with ease could be saved.

What can make the BMT in India more difficult for the patients?

BMT in India appears partially difficult for some patients and their families. Especially the foreign patients and such patients who are looking for the best economic treatment options. Insurance covers also do not provide a full cover on diseases which require BMT. India is already offering economic services for its patients in comparison to global treatment prices.

It involves a huge investment though but still, there are endless hospitals in India who are competing to strive and provide the best available treatment globally, within the country itself. BMT in India also involves those risks of transplant like in any other country. These complications can be mild to severe and sometimes life-threatening as well.

It includes:

•   Infections, organ injury, transplant rejections.

•   Allogenic transplants also include graft-versus-host disease in some cases which affects the skin, liver, eyes, lungs, and digestive system.

•   New cancer or even death in rare cases etc.

Related FAQs:

Q: Is it important for the patient and the donor to have the same blood group?

A: No blood group matching is not mandatory. Instead, HLA typing in DNA must match 6 to 10 major markers for an ideal match.

Q: Procedure of BMT in India or bone marrow donation requires any removal of the bone part?

A: No, BMT in India does not require any bone piece removal at any stage of the procedure. Only stem cells are obtained either from a blood sample or fluid present inside the bone.

Q: Any surgery is involved in bone marrow donation process?

A: In most of the cases of BMT in India, stem cells are obtained via peripheral blood stem cell donation without any surgery. Although, a very less fraction of nearly 5 to 9 percent of cases might involve a surgical procedure to obtain stem cells.

BMT in India- How can I get low-cost treatment

BMT in India- How can I get low-cost treatment
BMT in India- How can I get low-cost treatment

Looking for affordable BMT in India is really easy. India itself offers a wide range of quality and cost-effective treatment and procedure options. Further, reaching out the best economic hospital in India can be tricky but not difficult. There are several hospitals offering packages at economic prices for Bone Marrow Transplant in India. You may find several medical tourism companies to help you reach out the best hospital as per your need. 

Cost-efficacy of Bone Marrow Transplant in India?

There are many cost-effective treatment options available for Bone Marrow Transplant in India. It involves the complete replacement of damaged hematopoietic stem cell and this procedure is also known as HSCT. The donor’s hematopoietic stem cells regenerate the patient’s hematopoietic system over the time and makeup WBC, RBC, and platelets and the blood count reach the desired values. The most cost-effective But in India can be autologous stem cell transplant in which patient’s own healthy stem cells are re-infused during treatment. But every individual cannot be eligible for the same. Since this requires healthy stem cells and not the damaged ones to re-boost the system again. This procedure minimizes the time, cost and effort in finding a matching donor. Other than this peripheral blood and cord blood transplant are the available options.

Why is the cost of Bone Marrow Transplant in India more in few hospitals and low in others?

The high-cost variation of Bone Marrow Transplant in India among several hospitals is often linked with several factors. Some of these include poor insurance cover availability; different staging or diagnosis equipment and procedure costs because of the difference in facilities provided by each hospital etc. The costing of Bone Marrow Transplant in India is comparatively cheaper than offered by many other developed countries. Although, during BMT in India variation of cost can be felt even in HLAs compatibility testing of related or unrelated donors. So small-small variations in cost add up and make a huge difference. The best way is to opt for the hospital as per budget and facilities required this minimizes the hassle of dealing with finances at each step during the Bone Marrow Transplant procedure.

The cost of BMT in India, offered by each hospital is also impacted by the team of specialized professionals and high-tech equipment and other amenities the hospital possess.

How can the cost of Bone Marrow Transplant in India be further minimized?

By taking proper measures and precautions to avoid complications during and after Bone Marrow Transplant in India helps in minimizing the extra cost which adds up to the expenses. The occasional cases of stem cell rejection causing a complete failure of the procedure. It leads to an extension of hospitalization under aseptic conditions and further increases the cost of Bone Marrow Transplant as well.

Related FAQs:

1) Q: Is it really dangerous to undergo Bone Marrow Transplant procedure?

A: BMT procedure is completely safe although like any other procedure it does have some risks of developing complications. Stem cell engrafting failure in allogeneic transplant is the main risk though, it does not happen in all cases.

2) Q: Which Bone Marrow Transplant is best for my case? How do I confirm it?

A: Your treating physician is the best person to guide you on this after the complete analysis of your condition. You may also choose to discuss and get the second opinion about your diagnosis and treatment from another expert as well. Usually, a coordinator in every hospital is given the duty of clearing all your doubts.

3) Q: After how long I can get back to work after Bone Marrow Transplant in India?

A: Because of decreased immunity and increased risk of infections it is suggested always to avoid work and crowded places. Usually, a resting period of 3-6 months after an autologous transplant and 6-12 months after allogeneic transplant is recommended for complete recovery. During this time the body regains lost strength and immunity. Further, the resting period might vary depending upon complications if any or your health condition. You must always seek your treating physician’s advice before returning to work.

BMT in India- Hospitals have the highest Success Rate

BMT in India- Hospitals have the highest Success Rate
BMT in India- Hospitals have the highest Success Rate

The increasing medical advancements in recent years in India have taken the entire world by storm. Modern and advanced India is carving a niche for its own identity by providing effective and affordable medical treatments for such diseases which are a global issue these days. The cost-effectiveness of the medical procedures like BMT in India given by several hospitals is leading its way for medical tourism as well. A cut-throat competition given by India to several developed countries by charging just a fraction of the cost being charged by other counties is a huge transformation in the medical field.

Bone Marrow Transplant in India is offered by several hospitals which possess a team of trained medical professionals who have their specialization in hematology and oncology. To help and assist them there is another team of trained professionals including doctors and nurses etc. The high success rate of the procedure achieved by the hospitals is both due to good professionals as well as of the equipped diagnostic and treatment materials which are kept up to date as per the modern technology.

When you should go for a Bone Marrow Transplant in India?

Bone Marrow Transplant in India is far more economical and hassle-free. So go for it in case you are suffering from:

•   Damaged immune system which needs a regeneration which can be done by BMT.

•   A bone marrow degeneration caused by any genetic disease like Hurler’s syndrome or adrenoleukodystrophy etc.

•   The bone marrow malfunctioning caused by high dose chemotherapy or radiation to treat any brain tumor or any other cancers etc.

• Leukemia, Aplastic Anaemia, Sickle Cell Anemia, and other blood disorders which requires Bone Marrow Transplant to cure the condition.

Bone Marrow Transplant in India? What does it involve during the procedure?

There are several options available for BMT in India.

Some of them are listed below:

•   Autologous transplant: In this stem cells are obtained from the patient’s body itself.

•   Allogenic transplant: In this procedure, matching stem cells are obtained from their parents, siblings or any other unrelated donor.

•   Syngeneic transplant: In this procedure source of stem cells is the identical twin of the patient.

•   Umbilical cord transplant: This procedure involves the use of stem cells obtained from the umbilical cord of the newborn. These days several cord blood banks preserve the cords against some fees for a specific period and hence this cord can be used as a source for stem cells if required in future. This also reduces an effort and time to find a matching donor in the critical circumstances.

Related FAQs: 

Q: What is the survival percentage and success rate after Bone Marrow Transplant in India?

A: India has transformed a lot in the medical field. Bone Marrow Transplant in India today has reached a survival point of nearly 62 percent and the success rate of Bone Marrow Transplant is also increasing with the application of high tech modern technology in India. Every hospital dealing with Bone Marrow Transplant has a good success rate.

Q: What is done during the Bone Marrow Transplant procedure in India?

A: The procedure of Bone Marrow Transplant in India, involves a basic process of removal of damaged stem cells and is further replaced with healthy stem cells by transplantation. Healthy stem cells can either be obtained from a donor or preserved umbilical cord from the blood cord bank.

Q: What is the average procedure cost of Bone Marrow Transplant in India?

A: Bone Marrow Transplant cost in India varies specifically as per the patient’s need and also because of a variety of facilities offered by hospitals. Upon an average, the BMT in India cost varies between 10 lakhs to 35 lakhs, which is a comparatively affordable price offered in comparison to other countries. This range Bone Marrow Transplant in India further goes down in the government hospitals of Rajasthan. In the last few years, Bone Marrow Transplant in India has emerged as the most affordable option.

Are Bone Marrow Transplants Successful?

Are Bone Marrow Transplants Successful?
Are Bone Marrow Transplants Successful?

A bone marrow transplant(BMT) or also known as stem cell transplant recently is the only treatment for several types of cancers. Like Multiple Myeloma, Leukemia, some blood diseases, and for several kinds of Lymphomas etc. The bone marrow transplant cost also varies significantly for different cases as per the requirement of the disease treatment. In previous times, it was more often to term it as a bone marrow transplant because of extraction of stem cells from the bone marrow. However, these days stem cells can directly be extracted from the blood and due to that it is more commonly termed as stem cell transplant now. The advancement of the medical field is not just confined to stem cell extraction but it has also impacted its cost with several options available these days. Previously BMT success rate was too low but now with increasing requirement of the procedure efforts has been made along with several kinds of research to create better economic options with increasing bone marrow transplant success rate.

The BMT success rate varies along with its cost depending upon the requirement of the individual. If a transplant is done from your own body than it is an autologous transplant and if it involves a donor than it is an allogeneic transplant. Involvement of matching donor increases bone marrow transplant success rate.

Why is there a need for a bone marrow transplant?

With increasing numbers of blood and other disorders at times, a BMT is the most successful option in terms of curing disease.

Some of the cases needing high bone marrow transplant success rate include:

•     For complete replacement of damaged or diseased bone marrow cells

•     For providing new stem cells to help killing cancer cells.

•     For a safe and effective high dose chemotherapy or radiation treatment in few cancers followed by replacement of damaged bone marrow.

How a bone marrow transplant success rate can be evaluated?

A successful bone marrow transplant has a direct dependency on how closely the donor and recipient bone marrow matches. At times it becomes difficult to find a perfectly matching genetically same bone marrow from the unrelated donors which greatly affects BMT success rate.

Another hurdle is not the cost but instead an engraftment phase of the procedure which takes normally 10 to 28 days after the transplant. If this fails then the whole BMT success rate declines. So this phase is monitored closely and its success signs start with an increase in white blood cell count indicating that the blood cells are rising to normal being newly formed.

The complete success of the BMT varies from case to case considering several factors and complications. Although most of the transplants are successful with rare cases of failure which can further be minimized with preventions and proper monitoring.

Related FAQs:

1) Q: What are the new options available in bone marrow transplants?

A: Bone marrow transplant success rate, as well as treatment options, vary tremendously and it has raised the survival rates graph from zero to over 85%. Several options include cord blood transplants, haploidentical transplants, and reduced-intensity transplants etc.
 

2) Q: What happens to the bone marrow transplant success rate if healthcare team is unable to find a perfect match of bone marrow donor?

A: In that case, the following options are available for the increasing bone marrow transplant success rate:

• Haplotype mismatched or parentChild transplant: In this, a 50% matching donor including a parent, child, brother or a sister can be used instead of a complete 100% match.

•     Umbilical cord transplant: This is another option if a donor match could not be found. All around the world cancer centers use cord blood for stem cell or bone marrow transplant.

What are the first signs of lymphoma cancer?

What are the first signs of lymphoma cancer?
What are the first signs of lymphoma cancer?

Do you know? “Lymphoma Cancer” is the fifth leading cause of death in the United Kingdom! Yes, it is true. This makes it all the more necessary to know about it. We at BloodCancerCure aim to answer all your questions.

What is Lymphoma Cancer?

Cancer that starts from the lymphatic system is called “lymphoma Cancer”. The lymphatic system consists of lymph nodes and organs such as thymus, spleen etc. The lymphatic system plays a role in maintaining the immunity of an individual.
The lymphoma cancer is the tumor of the white blood cells in the bone marrow, lymph nodes and other components of the lymphatic system. There is no benign form of lymphoma cancer as it tends to spread to all parts of the body.
The difference between a lymphoma cancer and leukemia lies in its origins. A lymphoma cancer characteristically develops in lymphatic tissue mainly the lymph nodes of the thymus gland. On the other hand, leukemia is a type of blood cancer which first starts in bone marrow.

There are many subtypes of the Lymphoma Cancer but the two most common of them are Hodgkin’s and Non-Hodgkin’s Lymphoma

What are the signs and symptoms of Lymphoma Cancer?

Depending upon the subtypes of cancer, the spread and the stage of the disease, it could have a variety of symptoms such as:

•    Fever and Chills
•    Unintended weight loss
•    Loss of appetite
•    Body pains
•   Anaemia
•    Fatigue and weakness
•    Swelling of lymph nodes
•    Enlargement of the spleen or liver in some cases.

The studies have shown the close association of the disease with certain risk factors. There is an increased incidence among people who have a known history of exposure to certain chemicals and ionizing radiation. Another major known cause of the lymphoma cancer is the “Epstein Barr Virus”. This virus is known to affect mainly the immunocompromised individuals such as those suffering from HIV-AIDS, or human T-lymphocytic virus etc. Smoking, excessive consumption of red meat and tobacco may increase the risk of cancer.


How is Lymphoma Cancer diagnosed?

In order to diagnose any type of cancer or for that matter any kind of disease, the doctor first needs to carefully examine the patient’s symptoms and the complaints with which he/she approaches the doctor. The doctor does this by doing a complete physical examination of the patient.
The doctor or the physician then prescribes a number of diagnostic tests to confirm the disease.

In order to obtain the final diagnosis, the following tests can be done:
•    Complete blood counts
•    Bone marrow biopsy
•    Lymph node biopsy
•    Special imaging tests such as MRI, Ct scan, and PET scan


How is Lymphoma Cancer treated?

Cancer causes a number of complications for patients. These could be an increased incidence of infections (immunocompromised state), a decrease in the number of other blood cells etc. 
In mild cases, sometimes doctors prefer regular monitoring of the disease without any treatment or just giving symptomatic treatment

The major treatment modalities include:
• Chemotherapy
• Radiation therapy
•    Targeted therapy
•    Surgical removal of the enlarged spleen

Sometimes, there is an excessive amount of some plasma proteins in the blood which may cause problems. It is removed by a process known as “Plasmapheresis”. 
This cancer was once a critical and fatal condition. But, nowadays, with extensive research, this disease is almost curable. India is becoming a leading hub in all the new treatments at low costs with excellent results. Visit our website www.bloodcancercure.com for more information. 

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

Bone Marrow test cost in India

Bone Marrow test cost in India
Bone Marrow test cost in India

Bone Marrow is the soft gelatinous tissue found inside the bones of the human body. It is mainly responsible for the production and maturation of blood-forming stem cells in the body. These mature stem cells are then released into the peripheral bloodstream where they differentiate into the three types of blood cells, namely, the red blood cells, the white blood cells, and the platelets.

What is a Bone Marrow Test?

The bone marrow test or biopsy is a specialized diagnostic procedure in which a certain portion of the marrow tissue is obtained and is then tested under the microscope. It is a fairly regular procedure which is done to detect various blood-related disorders. These could be blood cancers (leukemia and lymphoma), anemia, Sickle Cell Anemia, Thalassemia, Neutropenia etc.

It basically gives a better idea of what is going on inside the body when the doctors are unable to find the answers with other specialized tests.

How often is this procedure done?

Due to its positive results, the test is done to know the exact cause of certain blood disorders. Also, it harbors Stem Cells. Stem cells are pluripotent cells which means that they can basically turn into any type of cells under the influence of certain growth factors.

The procedure is done by all the doctors, nurses and other health care professionals in the laboratories. The test consists of two procedures i.e. the bone marrow aspiration and the bone marrow biopsy.

In India, all the leading private hospitals, government hospitals and most of the well-equipped laboratories offer this test. It is a fairly safe and regular procedure. Doctors do it all the time.

How much does the test cost?

India is becoming one of the leading medical hubs in the world. Globally, it is earning respect in terms of medical services and the qualified medical staff. The doctors here are hardworking and well trained to perform all kinds of procedures.

In India, the cost of the bone marrow test depends upon various factors. The bone marrow test cost in India varies directly upon the type of facility (public or private), the city or patient’s location, and also the availability of the test.

The bone marrow test cost ranges from Rs. 500-5000 in India. This is obviously the average cost of the test.  The bone marrow test cost can increase in case of any unforeseen complication that might occur.

As per the regular privately purchased health insurance, usually, the bone marrow test cost is included in the coverage. The cost of the test is usually reimbursed to the patient. In India, the bone marrow test cost is sometimes subsidized by the government for those patients who cannot pay the amount. There are many hospitals which come under this subsidized low-cost bone marrow test in the country.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What is the Success rate of Bone Marrow Transplantation?

What is the success rate of bone marrow transplantation?
What is the success rate of bone marrow transplantation?

What do you mean by Bone Marrow Transplantation?

Let’s get back to basics, shall we? As we know that bone marrow is a highly specialized tissue which performs the important function of growth and differentiation of blood cells.

Bone marrow transplantation is a process in which a patient with diseased bone marrow receives a healthy marrow tissue from a donor. It is a very common procedure which is being performed by all leading private and public hospitals in India. Our doctors are very skilled and competent in bone marrow transplantation.

Why is the Bone Marrow Transplantation done?

Bone marrow tissue consists of blood cells and stem cells in their various stages of development. Stem cells have the capability of turning into any types of cells and tissue when stimulated with certain growth factors. After the growth and differentiation of these stem cells, the matured blood cells are released into the bloodstream.

In certain individuals, the BM is defective either due to certain genetic or congenital diseases such as sickle cell anemia, thalassemia, hurler’s syndrome etc. Also, it does not function properly in certain blood cancers such as aplastic anemia, leukemia, lymphoma, multiple myeloma etc.

Bone marrow transplantation provided done correctly, is considered to be a cure for many of these disorders.

How does Bone Marrow Transplantation work?

Due to certain types of cancer, there is excessive proliferation of certain lineages of the myeloid and lymphoid cells. This abnormal proliferation of immature blood cells hampers the normal functioning of the other cells. This results in the deficiency of other types of blood cells and as a result, these cause the symptoms.

Also, chemotherapy is highly toxic to the bone marrow. So, many cancer patients have prescribed the transplantation procedure usually before and after the cancer treatment.

When the patient’s bone marrow is replaced by a healthier one (after doing appropriate pre-operative matching), it starts performing the regular routine functions. This transplantation procedure is being done for many years and has shown excellent results in patients.

The donor can either be the patient himself (autologous), or some relative or an unknown donor (allogeneic), or patient’s identical twin (syngeneic). 

What is the success rate for Bone Marrow Transplantation?

Transplantation is a common procedure with high chances of survival. A patient who has undergone the procedure and is doing fine after 5 years without any complications is expected to live an additional 15 years as compared to the survival rate of the disease condition.

In recent studies, it has been observed that the success rate for an allogeneic bone marrow transplant is around 60-62%, which in medical world is pretty good. It is also found that around three out of every four patients survive the bone marrow transplantation.

Nowadays, there is a specific protocol for every procedure which is being followed by a hospital. Thus, the patient receives same quality of care from all the healthcare professionals.

What are the complications associated with the Bone Marrow Transplantation?

The first year is very important for BMT patients as this is the time most complications occur.

One of the most severe and important complications associated with the transplant is its tendency for rejection. This results in a cascade of complications known as the “Graft vs Host Disease”. This occurs due to the improper matching of the Human Leukocyte Antigen of the donor and the recipient tissue.

The patient is also severely immunocompromised due to the ongoing chemo and the radiotherapies so as a result, transplanting a new tissue into the human body makes it prone to infections.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What is the Bone Marrow treatment cost in India?

What is the bone marrow treatment cost in India?
What is the bone marrow treatment cost in India?

The bone marrow treatment involves the replacing the diseased or the cancerous bone marrow of the patient with a healthy one. The basic function of the bone marrow is to produce the blood-forming cells which undergo growth and differentiation to become mature blood cells. These blood cells are then released in the bloodstream as red blood cells, white blood cells and platelets mainly.

Why is Bone Marrow Transplant done?

A bone marrow transplant is a highly specific procedure which is used to treat a variety of disorders and diseases.

The treatment is being extensively used in patients with childhood leukemia and lymphoma. It is indicated in adults as well.

The transplant has also shown positive results for the treatment of various rare blood disorders and genetic diseases. These include sickle cell anemia, myelodysplastic syndromes, thalassemia etc.

What is the cost of Bone Marrow Transplant in India?

India is becoming a leading destination for patients all over the world to get their treatment done. India offers high-end medical technology and skilled doctors at prices greatly lower than their western counterparts.

Bone Marrow Transplantation cost depends upon the condition of the patient, the type of bone marrow transplant technique, doctor’s consultation fees and hospital charges. Cost of transplant is also affected by the accommodation charges, visa fees, travel costs etc. which additionally patient and their attendants have to bear.

It is generally estimated that the cost of bone marrow transplant is one-sixth in India as compared to western countries such as USA, UK etc. The distances in the world are getting shorter. People do not have to think twice before going to another country. This has led to rising in medical tourism all over the world and India is one of the most emerging destinations.

In India, the transplantation costs around 10-15 lakhs when the donor is obtained from the family. The costs increase when the donor is found out from the registry. The cost then goes up to 25-30 lakhs.

The treatment is very cost friendly as compared to other developed countries. Also, the treatment is very cost friendly for patients who do not have bone marrow transplant treatment available in this country.

Related FAQs:

1) Q: What is the bone marrow transplant cost in most of the hospitals in India?

A: Depending upon the patient condition and hospital opted the price varies, however, usually it ranges between 6 to 14 lakh.

2) Q: What happens next if bone marrow cancer is diagnosed?

A: After diagnosis, the first step is bone marrow harvesting. This is done by extraction of bone marrow for analysis and confirmation of the presence of cancerous cells. Post that chemotherapy is started which is further followed by bone marrow transplant.

3) Q: How much variation is there in bone marrow transplant cost in India and other countries?

A: In India, the bone marrow transplant cost is more economical than any other country. In real the Indian price is nearly half or sometimes one-third of the price offered in other western countries. Even all insurance companies do not cover the entire types of transplants at times. So the price variation massively affects the finances of the patient and the family. This makes India bone marrow transplant cost effective for real.

What exactly does a bone marrow transplant procedure look like?

What exactly does Bone Marrow Transplant procedure look like
What exactly does Bone Marrow Transplant procedure look like

The bone marrow is a crucial tissue in the body. Any problem with it shows very drastically on the entire body.

What is a Bone Marrow Transplant?

The bone marrow is a store for all types of hematopoietic stem cells. Any damage to this tissue is a direct hindrance to the blood cells. The blood cells perform various important functions in the body such as transport of oxygen and nutrients, fighting infections, maintaining the body temperature etc. the blood consists of various cells such as red blood cells, the white blood cells (plasma cells, lymphocytes, natural killer cells, leukocytes etc.), and the platelets.

When the bone marrow fails to produce the desired number of blood cells due to any reason, a doctor prescribes a bone marrow transplant. It works on the basic principle that replacing the diseased marrow with a healthy one obtained from a healthy compatible donor.

The diseases which debilitate bone marrow are aplastic anemia, sickle cell anemia, thalassemia, cancers such as leukemia, lymphoma, multiple myeloma or certain myelodysplastic syndromes.

What is required for a Bone Marrow Transplant procedure?

Any medical procedure which involves the exchange of an organ or a tissue or a substance for that matter requires a strict protocol. The success and the failure of the bone marrow transplant procedure depend on this.

Firstly, the donor. The patient whose bone marrow is not working properly is advised by the doctor to get a bone marrow transplant. Usually, all the blood relatives of the patient are examined to see if they are a match.

Matching is a very important step as it can really make or break a transplant. the most important component is the “HLA matching”. Human Leukocyte Antigen or HLA is a protein present on the cell surface. This protein or marker is used by the immune system to differentiate any cell from being foreign. If the HLA matching is not done correctly, the body rejects the tissue and results in a series of complications. The immune system mounts a full-blown attack on the foreign tissue.

How is the patient prepared for a Bone Marrow Transplant procedure?

Bone marrow transplant procedure takes a minimum of a week in the hospital. The patient and the donor’s family are asked to make suitable arrangements for their stay, leaves from the jobs, and other family members.

Doctors also run a full-blood and medical workup to eliminate all kinds of debilitating illnesses. The patient is required to complete his/her Chemotherapy before receiving the new stem cells so as to gain a better effect.

The recipient is generally immunocompromised till the new cells become active. In order to protect the patient from any kind of infection, he/she is kept in a place which is reserved for people receiving bone marrow transplants. This is done to reduce the chances of exposure to infectious agents.

What is the procedure for a Bone Marrow Transplant?

When all the tests are done, and all the formalities are completed, the doctor gives a red flag for the transplantation. A bone marrow transplant procedure is very much comparable to a blood transfusion.

In the case of an autologous transplant, the cells are collected before commencing the cancer treatment. In some cases, a patient is transfused with stem cells both before and after the procedure to achieve better results.

If the patient is receiving an allogeneic transplant, the cells are retrieved from the donor 1-2 days prior to the transplant.

The cells are taken with the help a needle which is inserted in the hip bone. The patient is usually given local anesthesia.

What is Leukapheresis?

It is a procedure in which the donor is given a certain drug which facilitates the movement of the stem cells from the bone marrow to the peripheral blood. This makes the harvesting of the tissue during the bone marrow transplant procedure easier.  The blood from the donor is then obtained through an intravenous (IV) line. It is connected to a machine which separates the stem cells from other components of the blood and returns the rest of it to the donor.

The next step in the bone marrow transplant procedure is the transfer of the stem cells in the recipient. The stem cells are directly made to flow into the heart using a central venous port which is installed in the upper right portion of the patient’s chest. The heart pumps the cells directly into the bloodstream from where it reaches the bone marrow. The most important part of the bone marrow transplant procedure is the establishment of stem cells in the bone marrow of the recipient.

The patient undergoes multiple sessions to help stem cells to properly integrate themselves to the body. this process is known as “Engraftment”.

The patient is closely monitored by doctors to look for any signs of rejection or other complications.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.