Bone Marrow Transplantation for Lymphoma

Bone Marrow Transplantation for Lymphoma
Bone Marrow Transplantation for Lymphoma

Lymphoma is a kind of cancer which develops because of the lymphocytes mainly. White blood cells which protect the body against several infections are a type of lymphocytes which get impaired in lymphoma. The lymphocyte gets accumulated in lymph nodes or spread to several body parts causing a traumatic condition of lymphoma. Its main origin is from the immune system itself since it involves lymphocytes and these multiply in uncontrolled numbers spreading to spleen bone marrow, thymus, lymph nodes etc.

Lymphoma is mainly divided into the following types:

•   Hodgkin Lymphoma

•   Non-Hodgkin lymphoma

Depending upon a specific type a particular bone marrow transplantation can be suggested by your physician for treatment. You must consider sharing all your previous medical history details with your physician before starting with any specific treatment in order to prevent any last moment complications.

Which different types of bone marrow transplantation can help in treating lymphomas?

Bone marrow transplantation helps in treating even the advanced staged lymphomas. But it requires a completed in detailed diagnostic analysis of the condition. Which can be done by an expert who is specialized in the diagnosis and treating cancers or lymphomas.

The three different transplant types are listed below based on its donor:

•   Syngeneic Transplant: In this, the stem cells are donated by an identical twin of the patient.

•   Autologous Transplant: In this, Stem cells are obtained from the patient itself. Healthy stem cells if present is used as a source of bone marrow transplantation in some cases.

•   Allogeneic Transplant: In this, a related or unrelated donor with a close match or complete match of stem cells is the source for transplant.

Depending upon case your physician can suggest the best suitable bone marrow transplant for you after a complete analysis of the condition.

What role does bone marrow transplantation play in lymphomas?

Bone marrow transplantation replaces the unhealthy or damaged blood-forming cells with the healthy ones. The process is termed as bone marrow transplant or stem cell transplant. It involves either autologous transplant in which cells are obtained from the patient itself or allogeneic transplant in which source of healthy stem cells is a related or unrelated donor.

In the case of Hodgkin’s Lymphoma autologous transplant is the most common type. It involves high dose chemotherapy sessions followed by a transplant. Although, chemo is required in mostly both kinds of transplants initially to kill the cancerous cells or lymphomas in the body. After that new cells are infused which travels inside the body to reach bones and reboot the process of blood cell production again.

Everything is done in a hospital under proper observation and measures are taken to prevent and minimize post-procedure complications.


Related FAQs:


1) Q: What are the different signs and symptoms of lymphomas?

A: Its signs include enlarged or swollen lymph nodes, chest pain, extreme fatigue, shortness of breath or even cough, abdominal swelling, occasional chills, and weight loss etc.


2) Q: Is there any difference between stem-cell transplant and bone marrow transplantation?

A: The main difference lies in the fact from where the donor cells are obtained. Like stem-cell transplant or peripheral blood stem-cell transplant involves extraction of cells from the peripheral or circulating blood of the body whereas in bone marrow transplantation the source is bone marrow itself. The procedure of stem-cell transplant is comparatively easy and involves quicker regeneration of new cells in the body.


3) Q: Which type of bone marrow transplantation are common for Hodgkin Lymphomas (HL)?

A: Autologous, as well as allogeneic bone marrow transplantation, are the most preferred ones for Hodgkin Lymphomas. But your physician can only suggest the best suitable type of bone marrow transplantation as per your case.

What are the first signs of lymphoma cancer?

What are the first signs of lymphoma cancer?
What are the first signs of lymphoma cancer?

Do you know? “Lymphoma Cancer” is the fifth leading cause of death in the United Kingdom! Yes, it is true. This makes it all the more necessary to know about it. We at BloodCancerCure aim to answer all your questions.

What is Lymphoma Cancer?

Cancer that starts from the lymphatic system is called “lymphoma Cancer”. The lymphatic system consists of lymph nodes and organs such as thymus, spleen etc. The lymphatic system plays a role in maintaining the immunity of an individual.
The lymphoma cancer is the tumor of the white blood cells in the bone marrow, lymph nodes and other components of the lymphatic system. There is no benign form of lymphoma cancer as it tends to spread to all parts of the body.
The difference between a lymphoma cancer and leukemia lies in its origins. A lymphoma cancer characteristically develops in lymphatic tissue mainly the lymph nodes of the thymus gland. On the other hand, leukemia is a type of blood cancer which first starts in bone marrow.

There are many subtypes of the Lymphoma Cancer but the two most common of them are Hodgkin’s and Non-Hodgkin’s Lymphoma

What are the signs and symptoms of Lymphoma Cancer?

Depending upon the subtypes of cancer, the spread and the stage of the disease, it could have a variety of symptoms such as:

•    Fever and Chills
•    Unintended weight loss
•    Loss of appetite
•    Body pains
•   Anaemia
•    Fatigue and weakness
•    Swelling of lymph nodes
•    Enlargement of the spleen or liver in some cases.

The studies have shown the close association of the disease with certain risk factors. There is an increased incidence among people who have a known history of exposure to certain chemicals and ionizing radiation. Another major known cause of the lymphoma cancer is the “Epstein Barr Virus”. This virus is known to affect mainly the immunocompromised individuals such as those suffering from HIV-AIDS, or human T-lymphocytic virus etc. Smoking, excessive consumption of red meat and tobacco may increase the risk of cancer.

How is Lymphoma Cancer diagnosed?

In order to diagnose any type of cancer or for that matter any kind of disease, the doctor first needs to carefully examine the patient’s symptoms and the complaints with which he/she approaches the doctor. The doctor does this by doing a complete physical examination of the patient.
The doctor or the physician then prescribes a number of diagnostic tests to confirm the disease.

In order to obtain the final diagnosis, the following tests can be done:
•    Complete blood counts
•    Bone marrow biopsy
•    Lymph node biopsy
•    Special imaging tests such as MRI, Ct scan, and PET scan

How is Lymphoma Cancer treated?

Cancer causes a number of complications for patients. These could be an increased incidence of infections (immunocompromised state), a decrease in the number of other blood cells etc. 
In mild cases, sometimes doctors prefer regular monitoring of the disease without any treatment or just giving symptomatic treatment

The major treatment modalities include:
•    Chemotherapy
•    Radiation therapy
•    Targeted therapy
•    Surgical removal of the enlarged spleen

Sometimes, there is an excessive amount of some plasma proteins in the blood which may cause problems. It is removed by a process known as “Plasmapheresis”. 
This cancer was once a critical and fatal condition. But, nowadays, with extensive research, this disease is almost curable. India is becoming a leading hub in all the new treatments at low costs with excellent results. Visit our website for more information. 

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.