Bone Marrow test cost in India

Bone Marrow test cost in India
Bone Marrow test cost in India

Bone Marrow is the soft gelatinous tissue found inside the bones of the human body. It is mainly responsible for the production and maturation of blood-forming stem cells in the body. These mature stem cells are then released into the peripheral bloodstream where they differentiate into the three types of blood cells, namely, the red blood cells, the white blood cells, and the platelets.

What is a Bone Marrow Test?

The bone marrow test or biopsy is a specialized diagnostic procedure in which a certain portion of the marrow tissue is obtained and is then tested under the microscope. It is a fairly regular procedure which is done to detect various blood-related disorders. These could be blood cancers (leukemia and lymphoma), anemia, Sickle Cell Anemia, Thalassemia, Neutropenia etc.

It basically gives a better idea of what is going on inside the body when the doctors are unable to find the answers with other specialized tests.

How often is this procedure done?

Due to its positive results, the test is done to know the exact cause of certain blood disorders. Also, it harbors Stem Cells. Stem cells are pluripotent cells which means that they can basically turn into any type of cells under the influence of certain growth factors.

The procedure is done by all the doctors, nurses and other health care professionals in the laboratories. The test consists of two procedures i.e. the bone marrow aspiration and the bone marrow biopsy.

In India, all the leading private hospitals, government hospitals and most of the well-equipped laboratories offer this test. It is a fairly safe and regular procedure. Doctors do it all the time.

How much does the test cost?

India is becoming one of the leading medical hubs in the world. Globally, it is earning respect in terms of medical services and the qualified medical staff. The doctors here are hardworking and well trained to perform all kinds of procedures.

In India, the cost of the bone marrow test depends upon various factors. The bone marrow test cost in India varies directly upon the type of facility (public or private), the city or patient’s location, and also the availability of the test.

The bone marrow test cost ranges from Rs. 500-5000 in India. This is obviously the average cost of the test.  The bone marrow test cost can increase in case of any unforeseen complication that might occur.

As per the regular privately purchased health insurance, usually, the bone marrow test cost is included in the coverage. The cost of the test is usually reimbursed to the patient. In India, the bone marrow test cost is sometimes subsidized by the government for those patients who cannot pay the amount. There are many hospitals which come under this subsidized low-cost bone marrow test in the country.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

Is Bone Marrow Cancer curable? What are the treatments?

Is bone marrow cancer curable? What are the treatments?
Is bone marrow cancer curable? What are the treatments?

What is a Cancer?

Cancer, as we know, is the abnormal proliferation of certain cells of the body which goes out of control. Cancer can develop practically in all parts of the body.

There are two types of cancerous lesions that are found in the human body.

These are:

Benign Cancer: It is the less dangerous one (unless it is impinging on surrounding tissues) as it doesn’t spread to other organs.

Malignant Cancer: It is the problematic one as it can rapidly spread to other tissues and can even cause a variety of other problems.

What is Bone Marrow Cancer?

Bone Marrow is the soft gelatinous substance present inside the bones. It is kind of like the manufacturing unit for production of blood cells in the body. It consists of many types of precursor blood cells, stem cells, mature cells etc.

It is actually the abnormal multiplication of any of these cells inside the bone marrow. Since the bone marrow has a direct connection with the blood supply, it can easily spread to other parts of the body.

What are the symptoms of Bone Marrow Cancer?

Any cancer for that matter does not have serious direct consequences. They usually create a problem with normal functioning of the body. in bone marrow cancer, the production of normal blood cells is hampered, or there is drastic increase in one type of the cell. As a result, the number and functioning of other cells are affected.

The following are the symptoms associated with it:

  • Anemia
  • Weight loss
  • Bleeding disorders
  • Fatigue and tiredness
  • Increase the frequency of infections
  • Immune-compromised state
  • Body pain
  • Bone weakness and frequent fractures
  • Kidney damage

What are the types of Bone Marrow Cancer?

The type of bone marrow cancer depends upon the type of the cell involved.

The types of cells are:

  • The red blood cells
  • The Platelets
  • The White blood cells which include lymphocytes, plasma cells, leukocytes etc.

Let us find out about some of the common types of bone marrow cancer.

Multiple Myeloma:
It is characterized by the excessive proliferation of plasma cells in the bone marrow. Plasma cells play a key role in forming antibodies against the various types of infections.

Leukemia:
This is characterized by a rapid increase in the number of white blood cells. This increase in the number of cells can be rapid (acute- ALL, AML) or slow-growing (chronic- CML, CLL).

Lymphoma:
This is the cancer of the lymphatic system. These can occur in many parts of the body.

This is of further two types: Hodgkin’s and Non-Hodgkin’s Lymphoma.

How is Bone Marrow Cancer diagnosed?

A doctor can make a number of diagnoses based on the symptoms that patients present with. The doctor can order various tests such as complete blood counts (CBCs), and certain imaging tests. Blood tests help to evaluate the blood counts, kidney function, and electrolyte levels. The imaging tests such as the MRI scan, CT scan or PET scan helps the doctor to evaluate the spread of the bone marrow cancer.

Another important technique to determine the type, severity and the spread of bone marrow cancer is the bone marrow biopsy. It is a confirmatory test for all the types of bone marrow cancers and blood disorders. The aspirated bone marrow is looked by a specialist under a microscope to get a clear picture of what is going on and plan treatment accordingly.

How is Bone Marrow Cancer treated?

The treatment of this cancer is very customizable according to each specific cancer. After the doctor determines the type, spread and the grade of cancer, an oncologist can design a specific course of treatment for a patient.

The two most common mode of treatment is Radiation therapy and Chemotherapy.

These can be used alone or along with each other as a part of adjuvant therapy. Both of these treatments are aimed at killing the cancer cells or stopping them from multiplying. The drugs may have targeted action on some kind of cancer cells.

For example, Imatinib (Gleevec) is a drug which is effective mainly for CML (a type of bone marrow cancer)

Patients generally start to lack the number of healthy blood cells required to perform normal day to body functions either due to bone marrow cancer treatment or due to the disease itself.

In such patients, physicians recommend a bone marrow transplant. it is a highly specialized procedure in which the healthy bone marrow is transferred into the deceased individual to take over the normal functions.

It is of three types: Allogenic, Autologous, and Syngeneic. 

 

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What is the Success rate of Bone Marrow Transplantation?

What is the success rate of bone marrow transplantation?
What is the success rate of bone marrow transplantation?

What do you mean by Bone Marrow Transplantation?

Let’s get back to basics, shall we? As we know that bone marrow is a highly specialized tissue which performs the important function of growth and differentiation of blood cells.

Bone marrow transplantation is a process in which a patient with diseased bone marrow receives a healthy marrow tissue from a donor. It is a very common procedure which is being performed by all leading private and public hospitals in India. Our doctors are very skilled and competent in bone marrow transplantation.

Why is the Bone Marrow Transplantation done?

Bone marrow tissue consists of blood cells and stem cells in their various stages of development. Stem cells have the capability of turning into any types of cells and tissue when stimulated with certain growth factors. After the growth and differentiation of these stem cells, the matured blood cells are released into the bloodstream.

In certain individuals, the BM is defective either due to certain genetic or congenital diseases such as sickle cell anemia, thalassemia, hurler’s syndrome etc. Also, it does not function properly in certain blood cancers such as aplastic anemia, leukemia, lymphoma, multiple myeloma etc.

Bone marrow transplantation provided done correctly, is considered to be a cure for many of these disorders.

How does Bone Marrow Transplantation work?

Due to certain types of cancer, there is excessive proliferation of certain lineages of the myeloid and lymphoid cells. This abnormal proliferation of immature blood cells hampers the normal functioning of the other cells. This results in the deficiency of other types of blood cells and as a result, these cause the symptoms.

Also, chemotherapy is highly toxic to the bone marrow. So, many cancer patients have prescribed the transplantation procedure usually before and after the cancer treatment.

When the patient’s bone marrow is replaced by a healthier one (after doing appropriate pre-operative matching), it starts performing the regular routine functions. This transplantation procedure is being done for many years and has shown excellent results in patients.

The donor can either be the patient himself (autologous), or some relative or an unknown donor (allogeneic), or patient’s identical twin (syngeneic). 

What is the success rate for Bone Marrow Transplantation?

Transplantation is a common procedure with high chances of survival. A patient who has undergone the procedure and is doing fine after 5 years without any complications is expected to live an additional 15 years as compared to the survival rate of the disease condition.

In recent studies, it has been observed that the success rate for an allogeneic bone marrow transplant is around 60-62%, which in medical world is pretty good. It is also found that around three out of every four patients survive the bone marrow transplantation.

Nowadays, there is a specific protocol for every procedure which is being followed by a hospital. Thus, the patient receives same quality of care from all the healthcare professionals.

What are the complications associated with the Bone Marrow Transplantation?

The first year is very important for BMT patients as this is the time most complications occur.

One of the most severe and important complications associated with the transplant is its tendency for rejection. This results in a cascade of complications known as the “Graft vs Host Disease”. This occurs due to the improper matching of the Human Leukocyte Antigen of the donor and the recipient tissue.

The patient is also severely immunocompromised due to the ongoing chemo and the radiotherapies so as a result, transplanting a new tissue into the human body makes it prone to infections.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What is the Bone Marrow treatment cost in India?

What is the bone marrow treatment cost in India?
What is the bone marrow treatment cost in India?

The bone marrow treatment involves the replacing the diseased or the cancerous bone marrow of the patient with a healthy one. The basic function of the bone marrow is to produce the blood-forming cells which undergo growth and differentiation to become mature blood cells. These blood cells are then released in the bloodstream as red blood cells, white blood cells and platelets mainly.

Why is Bone Marrow Transplant done?

A bone marrow transplant is a highly specific procedure which is used to treat a variety of disorders and diseases.

The treatment is being extensively used in patients with childhood leukemia and lymphoma. It is indicated in adults as well.

The transplant has also shown positive results for the treatment of various rare blood disorders and genetic diseases. These include sickle cell anemia, myelodysplastic syndromes, thalassemia etc.

What is the cost of Bone Marrow Transplant in India?

India is becoming a leading destination for patients all over the world to get their treatment done. India offers high-end medical technology and skilled doctors at prices greatly lower than their western counterparts.

Bone Marrow Transplantation cost depends upon the condition of the patient, the type of bone marrow transplant technique, doctor’s consultation fees and hospital charges. Cost of transplant is also affected by the accommodation charges, visa fees, travel costs etc. which additionally patient and their attendants have to bear.

It is generally estimated that the cost of bone marrow transplant is one-sixth in India as compared to western countries such as USA, UK etc. The distances in the world are getting shorter. People do not have to think twice before going to another country. This has led to rising in medical tourism all over the world and India is one of the most emerging destinations.

In India, the transplantation costs around 10-15 lakhs when the donor is obtained from the family. The costs increase when the donor is found out from the registry. The cost then goes up to 25-30 lakhs.

The treatment is very cost friendly as compared to other developed countries. Also, the treatment is very cost friendly for patients who do not have bone marrow transplant treatment available in this country.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

How painful is bone marrow biopsy?

How painful is bone marrow biopsy?
How painful is bone marrow biopsy?

What is a Biopsy?

Let us start with the most basic question: what is a biopsy? “Biopsy” is a type of invasive diagnostic and therapeutic procedure which involves the extraction of cells or tissues or a suspected mass from the body to examine it under the microscope. It is the most reliable way to confirm the diagnosis, type, and extent of cancer in the body.

What is Bone Marrow Biopsy?

Let us now come to the main topic. Bone marrow biopsy is an evaluation procedure in which the marrow tissue is obtained to be studied under the microscope. It is done to evaluate the different types of blood cells and the structure of the marrow.

Doctors advise a bone marrow biopsy when they find the discrepancy in the levels of WBCs or RBCs or platelets in the blood. It gives them a fair idea of the reason for this kind of discrepancy. A bone marrow biopsy has proven to be an effective diagnostic tool for various kinds of marrow and other blood cell-related disorders.

Why is the Bone Marrow Biopsy done?

Due to the reliability and sensitivity of the test, a bone marrow biopsy is considered to be a “gold standard” test for diagnosing and confirming any marrow related disorder. There are several conditions for which it is indicated. Mostly, it is used in diagnosing and determining the various types of blood cancers such as the Chronic Myeloid Leukaemia (CML), Multiple Myeloma, Lymphomas (both Hodgkin’s and Non-Hodgkin’s) etc. Also, it is done to find out the cause of severe persistent anemia, pancytopenia (decrease in the number of all three types of blood cells, namely, red cells, white cells, and platelets) or abnormal count of any of the three blood cells.

Marrow biopsy can sometimes prove useful to “evaluate a fever of unknown origin”, or to investigate abnormal bleeding or clotting times, to identify rare genetic diseases and some stem cell disorders and to monitor the iron overload conditions.

How is Bone Marrow Biopsy done?

Bone marrow biopsy is a fairly regular procedure with very fewer side-effects. The most commonly used sites for obtaining the marrow are the large pelvic bone near the hip (posterior iliac crest) and breastbone (sternum). In kids, marrow is generally taken from the shin bone (tibia).

The actual procedure of the bone marrow biopsy consists of two parts: the marrow aspiration (which obtains the sample of the liquid portion of the marrow) and the bone marrow biopsy (which is concerned with obtaining the solid portion). The biopsy can be performed in a hospital setting or a pathologic lab by the trained personnel.

The patient is made to lie on the side or on their back and then the area is numbed with a local anesthetic agent. The doctor inserts the needle and at this time the patient may experience sharp pain. The needle goes into the bone and extracts the bone marrow. The site is bandaged and the patient is good to go.

What needs to be kept in mind while undergoing the Bone Marrow Biopsy?

The patient should give a detailed and clear medical history to the doctor before getting started with the procedure. This should include any medications or allergies, any history of bleeding disorders, pregnancy status, or anxiety issues.

The patient should be calm and composed during the procedure. All the doubts or issue the patient might have should be taken care off by the physician in a satisfactory manner.

What are the risks associated with the Bone Marrow Biopsy?

As we already stated, bone marrow biopsy is a simple procedure. It can be performed without any difficulty with the help of a well-trained staff. But as we know nothing in this world is risk-free. It is reported that less than 1% of patients have suffered from some kind of complications with bone marrow biopsy.

Some of the common problems associated with the procedure are the allergy to anesthesia, infections or chronic pain. The major risks are haemorrhaging or excessive bleeding.

We believe we should address the particular side-effect of the procedure: “the chronic pain”. Ideally, on an average pain related to the procedure is short-lived. According to some studies, the duration of pain is said to be associated with the duration of and difficulty during the procedure.

A reduced level of anxiety and increased awareness of the procedure goes a long way in improving the outcomes.  

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What exactly does a bone marrow transplant procedure look like?

What exactly does Bone Marrow Transplant procedure look like
What exactly does Bone Marrow Transplant procedure look like

The bone marrow is a crucial tissue in the body. Any problem with it shows very drastically on the entire body.

What is a Bone Marrow Transplant?

The bone marrow is a store for all types of hematopoietic stem cells. Any damage to this tissue is a direct hindrance to the blood cells. The blood cells perform various important functions in the body such as transport of oxygen and nutrients, fighting infections, maintaining the body temperature etc. the blood consists of various cells such as red blood cells, the white blood cells (plasma cells, lymphocytes, natural killer cells, leukocytes etc.), and the platelets.

When the bone marrow fails to produce the desired number of blood cells due to any reason, a doctor prescribes a bone marrow transplant. It works on the basic principle that replacing the diseased marrow with a healthy one obtained from a healthy compatible donor.

The diseases which debilitate bone marrow are aplastic anemia, sickle cell anemia, thalassemia, cancers such as leukemia, lymphoma, multiple myeloma or certain myelodysplastic syndromes.

What is required for a Bone Marrow Transplant procedure?

Any medical procedure which involves the exchange of an organ or a tissue or a substance for that matter requires a strict protocol. The success and the failure of the bone marrow transplant procedure depend on this.

Firstly, the donor. The patient whose bone marrow is not working properly is advised by the doctor to get a bone marrow transplant. Usually, all the blood relatives of the patient are examined to see if they are a match.

Matching is a very important step as it can really make or break a transplant. the most important component is the “HLA matching”. Human Leukocyte Antigen or HLA is a protein present on the cell surface. This protein or marker is used by the immune system to differentiate any cell from being foreign. If the HLA matching is not done correctly, the body rejects the tissue and results in a series of complications. The immune system mounts a full-blown attack on the foreign tissue.

How is the patient prepared for a Bone Marrow Transplant procedure?

Bone marrow transplant procedure takes a minimum of a week in the hospital. The patient and the donor’s family are asked to make suitable arrangements for their stay, leaves from the jobs, and other family members.

Doctors also run a full-blood and medical workup to eliminate all kinds of debilitating illnesses. The patient is required to complete his/her Chemotherapy before receiving the new stem cells so as to gain a better effect.

The recipient is generally immunocompromised till the new cells become active. In order to protect the patient from any kind of infection, he/she is kept in a place which is reserved for people receiving bone marrow transplants. This is done to reduce the chances of exposure to infectious agents.

What is the procedure for a Bone Marrow Transplant?

When all the tests are done, and all the formalities are completed, the doctor gives a red flag for the transplantation. A bone marrow transplant procedure is very much comparable to a blood transfusion.

In the case of an autologous transplant, the cells are collected before commencing the cancer treatment. In some cases, a patient is transfused with stem cells both before and after the procedure to achieve better results.

If the patient is receiving an allogeneic transplant, the cells are retrieved from the donor 1-2 days prior to the transplant.

The cells are taken with the help a needle which is inserted in the hip bone. The patient is usually given local anesthesia.

What is Leukapheresis?

It is a procedure in which the donor is given a certain drug which facilitates the movement of the stem cells from the bone marrow to the peripheral blood. This makes the harvesting of the tissue during the bone marrow transplant procedure easier.  The blood from the donor is then obtained through an intravenous (IV) line. It is connected to a machine which separates the stem cells from other components of the blood and returns the rest of it to the donor.

The next step in the bone marrow transplant procedure is the transfer of the stem cells in the recipient. The stem cells are directly made to flow into the heart using a central venous port which is installed in the upper right portion of the patient’s chest. The heart pumps the cells directly into the bloodstream from where it reaches the bone marrow. The most important part of the bone marrow transplant procedure is the establishment of stem cells in the bone marrow of the recipient.

The patient undergoes multiple sessions to help stem cells to properly integrate themselves to the body. this process is known as “Engraftment”.

The patient is closely monitored by doctors to look for any signs of rejection or other complications.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.

What is a bone marrow? Why do some people need bone marrow transplants?

What is a bone marrow? Why do some people need bone marrow transplants?
What is a bone marrow? Why do some people need bone marrow transplants?

What do we mean by a Bone Marrow?

Let’s see! When we say bone marrow, we mean the soft, yellowish, gelatinous component present inside the bone. Bone is a hard structure and it is of two types mainly, the spongy and the cortical bone. The spongy bone is comparatively less hard and contains the active form of red bone marrow. On the other hand, cortical bone is strong and dense.

The red marrow consists of all the Myeloid cells and other precursor cells whereas the yellow bone marrow mainly consists of the fatty tissue.

Its function is the formation and maturation of new blood cells in the body, which is our main concern for now.

What are the diseases associated with the Bone Marrow?

Bone marrow is a tissue which performs a number of important functions. It acts as a reserve for stem cells and as well as storage of fatty tissue. Any problem with this issue and it can directly affect the working of the body.

Some of the diseases in which the bone marrow is compromised are:

Some of these diseases are genetic such as sickle cell anemia and thalassemia while the other is acquired such as aplastic anemia, myelodysplastic syndrome or polycythemia Vera etc. Generally, the bone marrow cancers can be both genetic and acquired as their exact cause is unknown.

What is a Bone Marrow Transplant?

A transplant is a medical term in which a diseased organ or tissue in a patient is replaced with a healthy one. In case a bone marrow becomes diseased or cancerous, the patient is advised by the doctor to get a bone marrow transplant.

It is a highly specialized and effective procedure to completely cure certain diseases, especially in children. In this procedure, the patient is transplanted with a new, healthy marrow to compensate for the earlier one’s inability to make new cells.

There are basically three types of bone marrow transplants that can be done:

Autologous Transplant: “Auto- means self”. The healthy tissue is obtained from the patient. This reduces any chances for rejection and other complications. It is usually done before and after the Chemotherapy treatment in cancer patients.

Allogenic Transplant: In this case, the bone marrow is obtained from a donor with proper matching protocols and is inserted into the diseased individual. It is done in cases where the recipient’s bone marrow is completely compromised and cannot produce any healthy cells. Allogenic transplant poses a high risk of infection and chances of rejection.

Syngeneic Transplant: It involves procuring the tissue from a healthy identical twin.


How is Bone Marrow Transplant done?

Due to successful results in treating various complex disorders and few risks involved, the bone marrow transplant is being done all over the world.
The first step in any transplant procedure is “finding a suitable donor”. The patient is put on a transplant list and is matched with a donor with the same blood type, HLA and other antigens compatible. Also, all the blood relatives of the patients are checked to see if their marrow matches with the recipient.

Once the donor is found, both the donor and the recipient undergo a surgery. The surgeon procures the marrow either from the sternum (breastbone) or the tibia in children. Before obtaining the tissue, the donor is given certain growth factors to promote the active proliferation of the cells.

Once it is obtained, it is stored and processed to be infused into the recipient. The bone marrow transplant is a fairly safe procedure, but it sure does have a few risks. The risks associated with a transplant are an infection, rejection or failure and the most importantly the “Graft vs Host Disease (GVD)”.

About BloodCancerCure:

BloodCancerCure is the world’s first such organization working 24*7 on helping blood cancer patients. BloodCancerCure works for patients across the world by providing the lowest cost for bone marrow transplants, chemotherapy, and Bone marrow test. You can contact at +91-8448533753 to talk to our experts at BloodCancerCure for BMT treatment in India.